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KMID : 0914820070070010038
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Journal of the Korean Gastric Cancer Association
2007 Volume.7 No. 1 p.38 ~ p.41
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Gastric Adenocarcinoma in Patient with Pernicious Anemia: A Case Report
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Kim Byung-Soo
Kim Jong-Won
Lee In-Kyu
Lee Hyuk-Joon
Yang Han-Kwang
Kim Dong-Chul
Kim Woo-Ho
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Abstract
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Increased risk of gastric cancer has been reported in patients with chronic atrophic gastritis that develops in conjunction with pernicious anemia. We report here a case of a gastric adenocarcinoma associated with pernicious anemia. A 40-year-old female patient had been diagnosed with anemia 6 years earlier at a local hospital. One month ago, she visited our hospital for aggravated dizziness and newly developed epigastric soreness. Her blood hemoglobin level was 4.2 g/dl, and a gastroscopic work-up for anemia discovered a 2.5-cm-sized, slightly elevated mucosal lesion at the anterior wall of the high body in the stomach. The biopsy of this lesion revealed a moderately-differentiated adenocarcinoma. She underwent a total gastrectomy with a Roux en Y esophagojejunostomy with D2 lymph node dissection. The final stage of the gastric carcinoma was identified as T1N0M0. Based on this experience, we recommend that a follow-up gastroscopy be performed in patients with pernicious anemia with atrophic gastritis because of the increased risk of gastric cancer in patients with pernicious anemia. (J Korean Gastric Cancer Assoc 2007;7:38-41)
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KEYWORD
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Pernicious anemia, Atrophic gastritis, Gastric cancer
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